Grape Seed Extract Activates Th1 Cells In Vitro
نویسندگان
چکیده
منابع مشابه
Grape seed extract activates Th1 cells in vitro.
Although flavonoids manifest a diverse range of biological activities, including antitumor and antiviral effects, the molecular mechanisms underlying these activities await elucidation. We hypothesize that the flavonoid constituents of a proprietary grape seed extract (GSE) that contains procyandins exert significant antiviral and antitumor effects, by inducing production of the Th1-derived cyt...
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In one study, 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were randomly assigned to a GSE group (n = 146) or control group (n = 141). As anticipated, after treatment, GSE resulted in significant reduction in MMCIMT progression, while MMCIMT and plaque score were stable and even increased with the control group. The numbe...
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The present study is focused on the investigation of in vitro angiogenic potential of grape seed extract (GSE). Human umbilical vein endothelial cells (HUVEC) in culture were used to assess the effect of GSE on proliferation, survival, matrix metalloproteinases (MMPs) secretion and capillary tube formation. Our data show that GSE significantly inhibited cell growth (< or =91%, P<0.001) and cell...
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PURPOSE Accumulating evidences suggest the beneficial effects of fruit-and-vegetable consumption in lowering the risk of various cancers, including colorectal cancer. Herein, we investigated the in vitro and in vivo anticancer effects and associated mechanisms of grape seed extract (GSE), a rich source of proanthocyanidins, against colorectal cancer. EXPERIMENTAL DESIGN Effects of GSE were ex...
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Background and aims. Promoting remineralization is the ultimate goal of clinical prevention of caries lesion. The present in vitro study aimed to investigate the effect of grape seed extract (GSE) on artificial enamel caries in primary human teeth. Materials and methods. Seventeen human sound primary incisors were sectioned mesiodistally. The tooth slices were placed in a demineralizing solutio...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2002
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cdli.9.2.470-476.2002